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. but new anti-HIV compounds are needed urgently to combat emerging viral resistance and reduce the side effects. AIDS constitutes one of. with zidovudine.start ART with nevirapine, lamivudine,. The syndrome is not a drug-speciﬁ c side-eﬀ ect,. efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.